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KMID : 0363220170550010045
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Korean Journal of Dermatology
2017 Volume.55 No. 1 p.45 ~ p.48
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Intractable Pruritus: A Presenting Sign of HIV Infection
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Seong Jun-Young
Kong Sook-Hyun
Suh Ho-Seok
Choi Yu-Sung
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Abstract
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To achieve early detection of HIV infection, physicians must be aware of symptoms related to HIV infection. Dermatologists, in particular, can play an important role, because more than 90% of patients infected with HIV will develop at least one type of dermatologic disorder, which may be the first indicator of the existence of infection. A 26-year-old male presented with a one-year history of intractable pruritus associated with multiple excoriations and small ulcers. Initially, his condition clinically resembled adult atopic dermatitis. However, no improvement was observed despite treatment including narrowband ultraviolet B (UVB), antihistamine, and topical and systemic corticosteroid. After a week, the patient developed seizures and was diagnosed with diffuse large B-cell lymphoma of the brain. HIV testing was performed, and the patient was revealed to be HIV-positive. He began highly active antiretroviral therapy (HAART), and the pruritus and skin condition improved dramatically. Herein, we report a case of HIV infection for which the presenting sign was intractable pruritus.
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KEYWORD
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Acquired immunodeficiency syndrome (AIDS), Human immunodeficiency virus (HIV), Pruritus
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